May Help With Parkinson’s Disease
In Parkinson’s Disease, loss of dopamine and oxidative stress are hallmarks of the disease.
By activating CB2 receptors, Beta-Caryophyllene also known as BCP, can inhibit dopamine loss and oxidative stress in the brain.
For example, BCP can protect against MPTP (a toxin used to destroy dopamine neurons in animal studies)-induced damage to the substantia nigra (the part of the brain most sensitive to dopamine loss in PD)
May Help Multiple Sclerosis
BCP may also help with Multiple Sclerosis (MS) by reducing TH1 and TH17 pro-inflammatory cytokines.
By increasing Treg anti-inflammatory cytokines (such as IL-10), BCP may help reduce the progression and symptoms of MS, such as neuropathy and pain.
Protects The Gut
BCP may help with Inflammatory Bowel Diseases (IBD).
For example, BCP can reduce inflammation in the colon by activating CB2 and PPAR-gamma receptors. These anti-inflammatory effects can be enhanced when combined with Curcumin,
May Improve Oral Hygiene
BCP may inhibit dental plaque buildup. It may also prevent gingivitis.
Is An Anti-Microbial
BCP has anti-bacterial activity. BCP has anti-fungal activity. BCP has anti-parasitic activity. BCP may also help prevent tick bites (from malaria) and mosquito bites (from the virus Aedes aegypti), reducing the chances of developing Yellow Fever, Dengue Fever and Chikungunya.
May Reduce Depression And Anxiety
BCP may reduce depressive and obsessive-compulsive symptoms.
It may also reduce anxiety (without affecting motor coordination) and may help with General Anxiety Disorder (GAD).
Helps With Sleep
BCP can decrease the time it takes to get to sleep and increase sleep time.
BCP may help relieve chronic pain and neuropathy. By working on the opioid system and endocannabinoid system, BCP can increase natural endorphins and reduce inflammation.
It may also be applied topically and locally to areas of pain.
BCP can help reduce muscle spasms and muscle pain. It may have synergistic effects with DHA against pain. It may also potentiate the analgesic action of morphine.
Also, BCP may increase testosterone and estrogen levels in those with chronic pain.